Dynamical Self-organization in Protein Folding

Authors

  • Antti Niemi Division of Theoretical Physics, Uppsala University, Sweden Laboratory of Mathematics and Theoretical Physics, CNRS, Tours, France

DOI:

https://doi.org/10.11145/167

Abstract

We propose that protein folding is due to a self-organization process, that can be described in terms of solitons, the paradigm self-organizers in numerous physical scenarios. We present a simple Hamiltonian energy function that supports solitons, and show how these solitons can be utilized to describe protein collapse. As an example, we consider two proteins, the myoglobin and a mainly-beta-stranded protein with PDB code 3LL1 and show how in both cases the process of collapse can be modeled, with sub-atomic precision, in termsВ  of explicit soliton profiles.

Downloads

Published

2013-05-13

Issue

Pilot Issue

Section

Conference Keynote Presentations

License

The journal Biomath Communications is an open access journal. All published articles are immeditely available online and the respective DOI link activated. All articles can be access for free and no reader registration of any sort is required. No fees are charged to authors for article submission or processing. Online publications are funded through volunteer work, donations and grants.

Authors who publish with this journal agree to the following terms:

  • Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License 4.0 that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
  • Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  • Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).