Methods and Information Technology Tools for Regulatorika of Living Systems
AbstractMethods and Information technology tools (using class of the functional-differential equations) to quantitative research regulatorika of living systems taking into account spatio-temporal organization, cooperativity, a competition for signals and the combined feedbackВ are developed. Methods of the qualitative and quantitative analysis of characteristic solutions of biosystems regulatorika equations using phase and parametrical portraits, calculations of Kolmogorov's entropy, Lyapunov's value, Hausdorff and higher dimensions have been constructed. Applying method of qualitative analysis it has been shown that regulatorika of living systems have the following regimes: rest, a steady stationary condition, self-oscillations, irregular fluctuations (dynamic chaos) and sharp destructive changes - "black hole" effect. The basic characteristics (quantity, sizes and its positions) of small regions with regular behavior in the field of dynamic chaos (r-windows) are investigated. It is developed program which oriented to quantitative research regulatory mechanisms of molecular-genetic, cellular, subcellular systems, an organism and populations. The received results can be used for the quantitative analyzing mechanisms of occurrence and development of chromosomal aberrations during malignant regeneration of cells, correction of clinical course of viral hepatitis and Acquired Immune Deficiency Syndrom (AIDS/HIV) development.
The journal Biomath Communications is an open access journal. All published articles are immeditely available online and the respective DOI link activated. All articles can be access for free and no reader registration of any sort is required. No fees are charged to authors for article submission or processing. Online publications are funded through volunteer work, donations and grants.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License 4.0 that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).