Dynamical analysis of Dengue and Chikungunya co-infection model

Abstract

This work is devoted to the study of transmission dynamics of Dengue
(DEN) and Chikungunya (CHK) viruses in a population. The cases of
CHK-DEN coinfection were reported in many countries and posed a serious
threat to public health sector globally [1], [2]. Thus, a coinfection model
has been developed and used to assess the impact of the spread of each disease
on the overall transmission. The dynamical analyses for the CHK-only
and DEN-only sub-models and the full (CHK-DEN) model revealed that
the models undergo backward bifurcation when the corresponding associated
reproduction number of the model is less than unity. Uncertainty and
sensitivity analyses (of the parameters of the model) are carried out to,
respectively, account for the eect of uncertainties and quantify the impact
of the variations or sensitivity of each parameter of the model on the
associated numerical simulations.