Computer System for Diagnostics of Disease Condition of an Organism Taking into Account the Basic Levels of Biosystem Organization
AbstractIn the given workВ the results of working out of theobject-oriented software for analyzingВ mechanisms of occurrence, development and consequences of illnesses of an organism by examples ofВ follicular cancer ofВ thyroid gland and hepatitis B based onВ the modeling backup for quantitative research of regulatory mechanisms functioningВ developed by authors at molecular-genetic, cellular, organ-tissue and organismal levels of living system organization and experience of construction of corresponding mathematical and computer models are considered.Applying methods of the qualitative analysis offunctional-differentialВ equations of mathematical models, the conditions for abnormalities occurrence in hormonal regulation of thyroid gland functions and in regulatorika of the interconnected activity of molecular-genetic systems between hepatocytes and hepatitis B virusВ are defined.В Software complexes for diagnostics, treatment and forecasting of diseases outcome are constructed taking into account the structurally-functional organization of cells, intercellular mutual relations and organismal regulation on concrete sites of considered organ and tissues. It allows to conduct computing experiments on habitual object for medical officers, to effectivelyВ interpret results ofcomputer modeling organism functioning at norm andВ anomalies, to develop the real scientifically-proved recommendations about improvement of organism conditionВ at diseases.
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