Electrical Properties of Blood in Patients with Type 2 Diabetes Рњellitus


  • Vasilka Paskova*
  • Nadia Antonova
  • Nino Chaushev
  • Irena Velcheva
  • Ivan Ivanov




The aim of the study was to investigate kinetics of blood conductivity in patients with type 2 diabetes mellitus under transient viscometric flow. The measurements were done by the rotational viscometer Contraves Low Shear 30 (Switzerland) with a concurrent measuring system MS 1/1, including a device, developed by the conductometric method with a software for measurement of conductivity of biological fluids (Data acquisition system) [1,2].В  The measurements of whole blood conductivity in a group of 13 patients were carried out at temperature 37в—¦C and were completed within 3 hours after blood withdrawal. The time variation of whole human blood conductivity and shear stresses were investigated at rectangular shaped Couette viscometric flow under electric field of 2 kHz. The kinetics of conductivity signals were recorded both under transient flow and after the complete stoppage of shearing at shear rates from 0 to 94.5 s-1. The experimental dependences of whole human blood conductivity were processed through the program Origin 61 by non-linear curve approximation of the growth and relaxation curves of the signal. The parameters of the equations, determined from the experimental data were analyzed as time characteristics of the transient organization of erythrocytes in red blood cells (RBC) aggregates at low shear rates or after complete flow stoppage and their desaggregation under high shear rates. The results obtained for the blood conductivity in time depends on the shear rate and on the hematocrit of the samples under transient flow. The results suggest that this technique may be used to clarify the mechanism of dynamics of RBC aggregates in patients with type 2 diabetes mellitus.






Conference Contributions